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White Papers / Tech Papers

Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS

High Resolution Accurate Mass (HRAM) Mass Spectrometry offers an alternative solution to provide peak purity assessment for small and large molecules.

Released By Almac Group

High Resolution Accurate Mass (HRAM) Mass Spectrometry offers an alternative solution to provide peak purity assessment for small and large molecules.

This technique offers both an indication of the peak’s purity and precise mass data for any observed impurities, enabling the generation of a tentative identity. HRAM also allows an understanding of the level of impurity present underneath the peak, making peak purity a more quantitative assessment than previous techniques.

In this paper, two example case studies are presented for peak purity determination.

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